Four-day plaque regrowth evaluation of a peptide chewing gum in a double-blind randomized clinical trial

Authors: Brian Kirkwood, Michael Miller, Jeffery Milleman, Kimberly Milleman Abstract Objective: Antimicrobial peptide, KSL-W, formulated as an antiplaque chewing gum(APCG), was tested to evaluate the dental plaque inhibition activity and safety in anIRB approved and FDA regulated 4-day plaque regrowth clinical study. Methods: This Phase 2 two-armed placebo-controlled, double blind, randomized(1:1), multiple dose, and single-center …

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